FZD4 Antikörper (PE)

Produktnummer ABIN2663398

Der Maus Monoklonal Anti-FZD4 Antikörper wurde für FACS validiert. Er ist geeignet, FZD4 in Proben von Human zu detektieren.

Kurzübersicht für FZD4 Antikörper (PE) (ABIN2663398)

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FZD4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: CH3A4A7

Produktdetails anti-FZD4 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu FZD4

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Andere Bezeichnung: CD344

Hintergrund: CD344 is a member of the Frizzled family, known as Frizzled-4 (Fz4, FZD4, hFz4, or FzE4). Ten frizzled member have been identified in humans. Human FZD4 gene has been mapped to chromosome 11q14-q21. FZD4 is a 48-53 kD seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins and norrie. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD4 is a neuronal stem cell marker and is also expressed on fetal neuronal progenitor cells and neuronal intestinal cells. Kidney, lung, brain and liver express abundant of FZD4. It has been reported that FZD4 controls retinal and inner ear angiogenesis, participates in the regulation of embryonic development, tissue and cell polarization and proliferation.

Pathways: WNT Signalweg, Hormone Transport, Sensory Perception of Sound